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The Wall Street Publication > Blog > World > NFL Week 4 predictions, picks: Our specialists face off on week’s high video games and bets, together with Packers-Cowboys
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NFL Week 4 predictions, picks: Our specialists face off on week’s high video games and bets, together with Packers-Cowboys

Editorial Board Published September 28, 2025
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NFL Week 4 predictions, picks: Our specialists face off on week’s high video games and bets, together with Packers-Cowboys
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There was loads of chaos in Week 3 of the 2025 NFL season. Sunday was the primary day in league historical past with a number of interceptions, blocked area targets and punts returned for touchdowns. They are saying the sport isn’t over till it’s over, and Week 3 actually confirmed that. 

The Los Angeles Rams (+3.5) had been up 26-7 over the Philadelphia Eagles within the second half, however misplaced and didn’t cowl the unfold because of a kind of aforementioned blocked area targets returned for a landing. Moreover, the Tampa Bay Buccaneers blew a 23-6 fourth-quarter lead in opposition to the New York Jets however had been capable of get the game-winning area aim, and we additionally noticed the Inexperienced Bay Packers, who appeared oh so dominant throughout the primary two weeks of the yr, blow a fourth-quarter result in the Cleveland Browns and the Denver Broncos blow a fourth-quarter result in the Los Angeles Chargers. It was insanity. 

Wager Week 4 at DraftKings Sportsbook, the place new customers get $200 in bonus bets and over $200 off NFL Sunday Ticket. Click on right here:

There are many different thrilling matchups on faucet for Week 4. We received issues began with a Seattle Seahawks win over the Arizona Cardinals on Thursday Evening Soccer, and the motion begins brilliant and early on Sunday with the primary ever NFL sport in Eire. Sunday wraps up with the “Micah Parsons Game,” because the star edge rusher leads the Packers in opposition to his former staff in Dallas on Sunday Evening Soccer.

Trying to wager on any of Sunday’s NFL video games? Who must you again and who must you be fading? CBS Sports activities writers Jordan Dajani and Steven Taranto are right here to interrupt down the largest video games of the weekend. Odds for these picks are from FanDuel Sportsbook, the place new customers can get $300 in bonus bets:

Dajani (Seahawks -1.5): The Seahawks, who’ve received seven straight conferences vs. the Cardinals, dropped a whopping 38 factors on the New Orleans Saints in simply the primary half final week. Sure, I do know it was the Saints, however that was nonetheless very spectacular. The Cardinals, however, common 276.3 yards of whole offense per sport, which is behind groups just like the Carolina Panthers and Browns, and Kyler Murray simply misplaced James Conner to a season-ending damage. Seattle is 6-1 in opposition to the unfold in its previous seven matchups vs. Arizona, so I’ll take them. Prediction: Seahawks 23, Cardinals 21

Taranto (Seahawks -1.5): Arizona is in an unenviable place right here, having to play one other sport simply 4 days after a gut-punch loss to the 49ers highlighted by continued points with drops for Marvin Harrison Jr. and a ugly season-ending damage to operating again James Conner. It’s unhealthy timing for the Cardinals to now run into the Seahawks, who’re coming off two wins in a row, together with a 44-13 beatdown of the Saints, and have received seven straight highway video games relationship again to Week 7 of 2024. Talking of seven, that’s the quantity of consecutive wins Seattle lords over Arizona relationship again to the tip of the 2021 season. Prediction: Seahawks 27, Cardinals 20

Editor’s Word: The Seahawks received 23-20. This submit has been up to date since this sport concluded.

Dajani (Vikings -2.5): I’m all in on Carson Wentz making a quarterback controversy in Minnesota, and this Vikings staff whooped the Cincinnati Bengals so unhealthy final week I feel they’ve been relegated to the UFL. The Steelers wanted the New England Patriots to show the ball over 5 occasions to win their Week 3 matchup, as Aaron Rodgers and Co. haven’t appeared good for the reason that season opener. Do you know the Vikings are 4-0 in worldwide video games? Now you do. Prediction: Vikings 16, Steelers 12

Taranto (Steelers +2.5): Kevin O’Connell has sprinkled pixie mud on one more quarterback written off as broken items, as Carson Wentz turned in a efficiency that turned again the clock to his early days on the Eagles in a 48-10 win over the Bengals. However the offense’s efficiency was complemented by an excellent defensive efficiency with a number of touchdowns by Brian Flores’ unit, which isn’t sustainable in opposition to a staff just like the Steelers that isn’t down its backup quarterback and enters this sport on the energy of a 2-1 document. A comparatively impartial web site of a sport on overseas soil (the Rooney household’s deep ties to Eire however) may be preferable to having to play in Pittsburgh itself, however I don’t assume that’s going to be sufficient to maintain the Wentz Wagon revival rolling. Prediction: Steelers 24, Vikings 10

Philadelphia Eagles (-3.5) at Tampa Bay Buccaneers

Dajani (Eagles -3.5): The Buccaneers are undefeated, 4-1 in opposition to Jalen Hurts, enjoying at house AND getting the hook at +3.5? Looks as if an auto-bet, proper? No! It’s a lure. Baker Mayfield has misplaced two beginning offensive linemen, and vast receiver Mike Evans has been dominated out with a hamstring damage. Saquon Barkley hasn’t appeared like an MVP candidate by means of three video games, however that’s high-quality. I’m taking a look at A.J. Brown to be an element on this one. He had 109 receiving yards simply within the second half final week. Prediction: Eagles 27, Buccaneers 23

Taranto (Buccaneers +3.5): Generally, historical past is simply an excessive amount of to beat. The Bucs will at all times be capable to boast that Ronde Barber shut down The Vet within the 2002 NFC Championship Sport in opposition to the Eagles, and this technology of Eagles — for all their dominance in any other case — struggles in opposition to this present iteration of Tampa Bay soccer. The Buccaneers have handed the Eagles two playoff losses previously 5 years, and beat them like a drum of their final common season matchup round this time a yr in the past. All of these video games had been performed in Tampa, making Raymond James Stadium a home of horrors for Jalen Hurts & Co., who’re presently successful extra on sheer expertise than they’re on ingenuity or creativity on offense. Prediction: Buccaneers 28, Eagles 16

Dajani (Rams -3.5): The Colts are 3-0 ATS whereas the Rams are 2-1 ATS. The hook appears enticing, however the Rams are simply the most effective staff the Colts have performed up to now. I’m nervous about Indy’s secondary after the Colts misplaced Kenny Moore to damage, and DeForest Buckner missed observe Wednesday resulting from a again damage. Right here’s the important thing stat to know: 3-0 groups as underdogs vs. non 3-0 groups are 1-10 ATS since 2014. Loopy, proper? Prediction: Rams 30, Colts 24

Taranto (Colts +3.5): Those that have wished to rationalize Daniel Jones enjoying like among the best quarterbacks within the NFL to begin the season have cited how his excellent performances have come in opposition to lesser competitors, specifically the Dolphins and Titans, whose head coaches are each on the brink. That received’t be the case in opposition to the Rams, however the Rams utterly blowing it in opposition to the Eagles final week is unquestionably a blow to that staff’s psyche. Now, they’re up in opposition to a Colts staff with all the arrogance on the earth — and a quarterback who’s now doing all of the issues everybody in New York mentioned he couldn’t do. Prediction: Colts 24, Rams 17

Agent’s Take: 2025 contract-year gamers to observe — might Daniel Jones turn into the subsequent $30 million QB?

Joel Corry

Dajani (Chiefs +2.5): The Ravens had been merely outplayed by a proficient offense that took benefit of the truth that Baltimore was lacking three necessary starters on protection. The Chiefs are anticipated to get Xavier Worthy again this week, which is a large elevate. I don’t know if Kyle Van Noy and Nnamdi Madubuike can be again for Baltimore. Patrick Mahomes is 11-5 SU and 12-3-1 ATS in his profession as an underdog, together with playoffs. He’s 5-1 all time in opposition to Lamar Jackson, so I’ll take the Chiefs at plus cash. Prediction: Chiefs 26, Ravens 23

Taranto (Ravens -2.5): This can be a matchup primarily based on status and never on the precise state of every of those two groups. The Chiefs received their first win of the season in Week 3, however they didn’t precisely grasp a quantity on a awful Giants staff and Steve Spagnuolo’s protection didn’t need to do something particularly artistic to stymie a deep-ball-or-nothing Giants offense. The Ravens are 1-2 on account of how in each video games they’ve performed in opposition to good competitors, their protection hasn’t been capable of cease anybody. The distinction is that in comparison with the Chiefs, the Ravens can rating, as they’ve put up no less than 30 factors in every of their three video games to this point this yr. Prediction: Ravens 27, Chiefs 20

Inexperienced Bay Packers (-6.5) at Dallas Cowboys (SNF)

Dajani (Packers -6.5): The Packers utterly bungled that matchup vs. the Browns, however they’re arrange for a rebound efficiency in Dallas. This Cowboys protection is horrible. They rank backside six in yards allowed per sport (397.7) and factors allowed per sport (30.7). Over the previous two video games, the Cowboys secondary has allowed quarterbacks to finish 71% of their throws for 360 yards per sport, seven touchdowns and one interception. Plus, CeeDee Lamb is predicted to be out resulting from his excessive ankle sprain. Yikes. Matt LaFleur is 22-11-1 ATS in prime-time video games — the most effective cowl share by a head coach since 2000. His staff coated vs. Washington on “Thursday Night Football” a pair weeks in the past, and can accomplish that once more on Sunday evening. Prediction: Packers 27, Cowboys 17

Taranto (Packers -6.5): This can be a traditional revenge sport the place the chickens come house to roost. With the Cowboys’ commerce of Micah Parsons leaving them with none actual menace of a move rush, their secondary hasn’t been capable of be as aggressive as they’ve been previously, and now they will’t cowl a soul. Dallas’ defensive performances in opposition to offensively-challenged Giants and Bears groups bode very poorly for them in opposition to the Packers, who’ve at all times been a well-oiled machine on offense and who’ve at all times been a horrible matchup for Dallas specifically. Add CeeDee Lamb’s damage to the combo, and Dak Prescott‘s particular person heroics may not be sufficient to save lots of the Cowboys from the results of Jerry Jones hardballing his greatest participant in contract negotiations to the purpose of alienating him. Prediction: Packers 41, Cowboys 13

New York Jets at Miami Dolphins (-2.5) (MNF)

Dajani (Dolphins -2.5): The Dolphins confirmed some combat in opposition to the Buffalo Payments final week. Mike McDaniel is teaching for his job, and he can nonetheless beat lesser groups with velocity. The Jets needs to be a well-liked upset choose this week, however the Dolphins received fairly the mini-bye having performed final Thursday evening. Prediction: Dolphins 17, Jets 13

Taranto (Jets +2.5): It’s straightforward to chew on the “Same Old Jets” narrative, however this specific iteration of Gang Inexperienced strikes me as a little bit totally different from years’ previous. Whereas Week 2 supplied extra of the identical when it comes to the Jets trying utterly hapless and incompetent, their different two video games this yr have each been rip-your-heart-out losses determined by being on the unsuitable finish of a late area aim. The Dolphins could also be coming off a aggressive effort in opposition to the Payments that stabilized the scenario surrounding embattled coach Mike McDaniel, but when the Jets can handle to get on Miami early, I feel they may be capable to frustrate them and make them stop. Prediction: Jets 23, Dolphins 10

Cincinnati Bengals at Denver Broncos (-7.5) (MNF)

Dajani (Broncos -7.5): I’ve been a sucker for the Broncos this yr. They coated for me in Week 1, misplaced to the Colts on a bogus penalty in Week 2 after which gave away a fourth-quarter result in Justin Herbert and the Chargers on Sunday. I went again and watched the movie on Bo Nix; his mechanics look off, as he missed three would-be deep-shot touchdowns. I nonetheless place confidence in him. In any case, he’s 3-0 following a two-game dropping streak, with the Broncos outscoring opponents 102-13 in these video games. This Denver squad wants a very good sport in opposition to a staff coming off a 48-10 loss to Carson Wentz. Prediction: Broncos 30, Bengals 20

Taranto (Broncos -7.5): I’m going to echo what Jordan mentioned right here in that I lack confidence in Bo Nix, however really feel pretty good about the remainder of the Broncos as a complete. Denver is at all times a troublesome place to play for visiting groups, particularly one coping with as a lot adversity now because the Bengals presently are. Even when Jake Browning will get off the mat after final week, it’s going to take a Herculean effort for him to get the most effective of Sean Payton. Prediction: Broncos 34, Bengals 17

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