HOUSTON — Ricky Pearsall is out a fourth straight sport, and Brandon Aiyuk’s comeback stays at the very least every week away, however the 49ers are debuting a reinforcement at vast receiver at this time on the Texans.
Rookie fourth-round choose Jordan Watkins is suiting up for his first sport, becoming a member of a unit that consists at this time of Jauan Jennings, Kendrick Bourne, Demarcus Robinson and Skyy Moore. Watkins’ profession has been delayed by calf and ankle accidents.
All of the 49ers’ cornerbacks are also suiting up regardless of damage issues hovering over Deommodore Lenoir, Renardo Inexperienced and Upton Stout.
Out for the 49ers are Pearsall, quarterback Brock Purdy, middle Jake Brendel, rookie Jordan James, defensive sort out C.J. West and defensive ends Bryce Huff and Yetur Gross-Matos.
The Texans are with out two of their high vast receivers, Nico Collins and Christian Kirk. Additionally out for Houston are offensive tackles Trent Brown (the cousin of 49ers rookie defensive sort out Alfred Collins) and Jarrett Kingston (2024 sixth-round choose by the 49ers), defensive finish Darrell Taylor, and quarterback Graham Mertz.
The 49ers (5-2) can take over sole possession of first place within the NFC West with a victory; the Los Angeles Rams (5-2) and the Seattle Seahawks (5-2) are each on byes.
The Texans (2-4) are enjoying their first house sport since a 26-0 shutout of Tennessee on Sept. 28.
Initially Revealed: October 26, 2025 at 9:11 AM PDT
