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The Wall Street Publication > Blog > Lifestyle > CVS Caremark drops protection of common weight reduction drug
Lifestyle

CVS Caremark drops protection of common weight reduction drug

Editorial Board Published July 8, 2025
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CVS Caremark drops protection of common weight reduction drug
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CVS Caremark, one of many three main pharmacy profit managers (PBM) within the U.S., stopped protection for Eli Lilly’s common weight-loss drug Zepbound, blaming medication prefer it for driving up total plan prices. 

GLP-1 merchandise, initially developed to deal with sort 2 diabetes, however at the moment are FDA-approved particularly for weight problems underneath model names like Wegovy and Zepbound, are “significantly contributing to overall plan costs”, CVS spokesperson Phillip Blando instructed FOX Enterprise. Eradicating protection of the drug will end in an estimated consumer financial savings of 10% to fifteen% 12 months over 12 months within the anti-obesity medicine area for its purchasers who select to cowl these drugs for weight reduction, in keeping with Blando. 

Zepbound, the model identify for Eli Lilly’s tirzepatide, was permitted by the FDA in 2023 for power weight administration in adults with weight problems or chubby with weight-related medical issues. Tirzepatide was already permitted to deal with sort 2 diabetes and was offered underneath the model identify Mounjaro. 

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A “Drive-Thru Pharmacy” signal is displayed outdoors of a CVS Caremark Corp. retailer in Dallas, Texas, U.S., on Friday, Feb. 7, 2014.  (Ben Torres/Bloomberg through Getty Photos / Getty Photos)

Zepbound was broadly seen as a game-changer within the struggle towards weight problems, after individuals in a late-stage examine misplaced as much as 1 / 4 of their physique weight – making it simpler than Wegovy.

Blando mentioned the “egregiously high list prices” for GLP-1 merchandise which are set by drug producers are “the single biggest barrier to patient access.”

“Many payers, including Medicare and numerous state benefit plans, have declined to cover GLP-1s for weight loss because of the unsustainably high prices set by brand pharma,” he mentioned. 

Nevertheless, there’ll nonetheless be exceptions if the drug is deemed a “medical necessity.” That exemption can be reviewed “on a case-by-case basis,” in keeping with Blando.

CVS Caremark is a subsidiary of CVS Well being Corp., which additionally owns CVS Pharmacy. As a pharmacy profit supervisor, CVS Caremark primarily acts as a negotiator between pharmacies, insurers and drug producers throughout the prescription drug provide chain. PBMs negotiate with drug producers and pharmacies to determine how a lot medicines value, which medication individuals can get and which pharmacies are a part of their community. 

CVS pharmacy sign above entrance to store with people walking past

Pedestrians stroll previous a CVS Caremark Corp. retailer in New York, U.S., on Tuesday, April 30, 2013. CVS Caremark Corp. is scheduled to launch earnings information on Might 1. Photographer: Victor J. Blue/Bloomberg through Getty Photos

Pharmaceutical giants have been important of PBMs, saying their position wants to alter. Eli Lilly beforehand instructed FOX Enterprise that the one method to decrease costs for U.S. customers is that if “intermediaries take less for themselves.” 

Gastroenterologist and weight problems medication specialist Dr. Christopher McGowan instructed FOX Enterprise that CVS Caremark’s determination to drop protection of the drug is “deeply disruptive for patients who are already stable and thriving on the medication.” 

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“We’re now seeing insurance policy override medical judgment – forcing patients to switch to an alternative that, while still effective, has been shown in head-to-head trials to produce less weight loss than Zepbound,” McGowan mentioned. 

McGowan highlighted that GLP-1 drugs “are not interchangeable in practice, even if they appear similar on paper.” He mentioned switching drugs “mid-journey can reverse hard-won progress.”

“For many, this isn’t just a simple substitution. It’s a high-stakes change that can affect long-term outcomes, trigger weight regain, or introduce new side effects,” McGowan mentioned. 

This goes past CVS Caremark, in keeping with McGowan, who is worried that its determination with Zepbound “underscores a troubling trend” by which “financial contracts between benefit managers and drug manufacturers are increasingly shaping clinical decisions.” 

An Eli Lilly & Co. Zepbound injection

An Eli Lilly & Co. Zepbound injection pen organized within the Brooklyn borough of New York, US, on Thursday, March 28, 2024.  (Shelby Knowles/Bloomberg through Getty Photos / Getty Photos)

This implies sufferers with fewer decisions not due to what’s greatest for his or her well being, however due to behind-the-scenes rebate offers, he continued. 

“In obesity care, continuity matters. Once a patient finds a medication that works, preserving that success should be the priority,” he mentioned. “Instead, we’re seeing progress disrupted and patients forced to navigate treatment changes they never asked for.”

Eli Lilly instructed FOX Enterprise that the corporate is dedicated to making sure sufferers have entry to the therapy they want. 

“While not all CVS Caremark plans are impacted, we’ve made robust efforts to proactively communicate with many of the patients who may be affected and provided clear next steps through our support programs,” Lilly mentioned in a press release, including that the corporate is encouraging sufferers to talk with their healthcare suppliers about medical necessity exceptions or different protection pathways. It has additionally added assets on its web site. 

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If prospects do lose protection, Eli Lilly mentioned it expanded entry by way of LillyDirect’s Self Pay Pharmacy Options, which is the corporate’s self-pay program, which removes some third-party provide chain entities, providing sufferers with out protection medication at a reduction. 

The pharmaceutical large mentioned a affected person that is prescribed Zepbound and wishes entry to it with out going by way of their medical health insurance can get single-dose vials for round $500.

TAGGED:CaremarkCoverageCVSdropsdrugLosspopularWeight
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